Surfactant
نویسندگان
چکیده
منابع مشابه
Surfactant and its Role
تنفس مهمترین وظیفه نوزاد بلافاصله بعد از تولد است و انجام تنفس مستلزم تکامل طبیعی ریه دوران جنینی می باشد.
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At present, exogenous surfactant replacement therapy and mechanical ventilation (MV) remain the ‘Standard of Care’ while treating such infants. However, this requires endotracheal intubation – an invasive procedure associated with complications. Moreover, the skills required to intubate very small babies are not universally available and may vary among the healthcare professionals even in devel...
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Aspects of pulmonary surfactant are reviewed from a biochemical perspective. The major emphasis is on the lipid components of surfactant. Topics reviewed include surfactant composition, cellular and subcellular sites as well as pathways of biosynthesis of phosphatidylcholine, disaturated phosphatidylcholine and phosphatidylglycerol. The surfactant system in the developing fetus and neonate is c...
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Pulmonary surfactant is a complex mixture of lipids and proteins that, by modulating surface tension during breathing, prevents alveolar collapse at exhalation and overdistention at inspiration. Surfactant is synthesized by type II pneumocytes, assembled in lamellar bodies and secreted at the air-liquid interface of the alveolus. This surface-active material is re-uptaken by alveolar type II ce...
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ژورنال
عنوان ژورنال: Neonatology today
سال: 2021
ISSN: ['1932-7137', '1932-7129']
DOI: https://doi.org/10.51362/neonatology.today/202131635153